Advate
Advate
| Product Specs | Advate |
|---|---|
| Manufacturer Name | Takeda |
| Description | ADVATE is a recombinant antihemophilic factor indicated for use in children and adults with hemophilia A. |
| Indications for Adults: | |
|
Control and Prevention of Bleeding Episodes |
Yes |
|
Perioperative Management |
Yes |
|
Routine Prophylaxis to Prevent or Reduce the Frequency of Bleeding Episodes |
Yes |
| Indications for Children: | |
|
Control and Prevention of Bleeding Episodes |
Yes |
|
Perioperative Management |
Yes |
|
Routine Prophylaxis to Prevent or Reduce the Frequency of Bleeding Episodes |
Yes |
| Contraindications Nutrient in Cell Culture | Do not use in patients who have lifethreatening hypersensitivity reactions, including anaphylaxis, to mouse or hamster protein or other constituents of the product (mannitol, trehalose, sodium chloride, histidine, Tris, calcium chloride, polysorbate 80, and/or glutathione). |
| Stabilizer in Final Formulation | mannitol, trehalose, sodium chloride, histidine, Tris, calcium chloride, polysorbate 80, and glutathione. |
| Viral Safety Process | Immunoaffinity chromatography; solvent/detergent |
| Product Half-Life | 12.0 ± 4.2 hours |
| Product Recovery Percentage Mean incremental recovery IR (IU/dL per IU/kg) | 2.6 ± 0.5 |
| Storage Requirements |
|
| Shelf Life | 24 months from manufactured date or 6 months at room temperature |
| Nominal Vial Size & Diluent Volume | 2 mL, 5mL |
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